Description
Altrenogest acts similarly to the natural hormone progesterone by
suppressing the normal sexual cycle and preventing signs of heat and
ovulation. Mares return to heat and release natural hormones again
once treatment stops. Treatment with altrenogest makes it possible to
finely regulate the breeding of mares.
The newer injectable form has recently been developed.
Pharmacokinetic studies have shown blood levels of altrenogest are
maintained for 5 – 7 days following administration of the injection.
Studies have been conducted to support supression of oestrus in cycling
mares for 5 – 7 days follwing administration of Readyserve Injection.
INDICATIONS
Oral Liquid: 1. For regulation and control of the breeding cycle of mares
a) To induce ovulatory oestrus early in the breeding season in mares
where some follicular activity exists
b) To suppress oestrus either during prolonged oestrus or in normally
cycling mares
c) To control the ovarian cycle in breeding mares to allow the most
efficient use of the stallion
2. For the maintenance of pregnancy in habitually aborting mares, or
mares at risk of early embryonic death or abortion, where progesterone
deficiency is thought to be the underlying cause.
Injection: For the suppresion of oestrus in normally cycling mares for
5 – 7 days. Can also be used for maintenance of pregnancy. Administer
every 5 – 7 days.
DOSAGE AND ADMINISTRATION
Oral Liquid: Administer 1 mL per 50 kg bodyweight (0.044 mg/kg
altrenogest) daily.
1. For regulation and control of the breeding cycle of mares
a) To induce ovulatory oestrus or to induce cyclical ovarian activity
in mares with some follicular activity early in the breeding season;
administer daily for 10 consecutive days
b) To suppress oestrus in normally cycling mares; administer daily for
15 consecutive days. To suppress prolonged oestrus; administer daily for
10 consecutive days.
c) To control the breeding cycle of mares to allow the most efficient use
of the stallion; administer daily for 15 consecutive days.
2. For the maintenance of pregnancy in habitually aborting mares, or
mares at risk of early embryonic death or abortion; administer daily
from the 2nd or 3rd day after ovulation in the mated or inseminated
mare, continuing daily until day 120 of gestation.
NOTE: Ultrasound scanning to confirm pregnancy is recommended
on day 14 or 15 after ovulation. If the mare is not pregnant,
cease READYSERVE administration and administer an injection of
prostaglandin F2α to destroy any remnant luteal tissue, allowing the
mare to return to oestrus and be re-mated.
WARNINGS
Contraindications: Not for use in stallions or geldings. Contraindicated
for use in mares with uterine infections.
Feed must be destroyed and not given to any other animal. Product
must be added to the feed immediately prior to consumption and feed
is not to be stored.
Meat Withholding Period: Oral Liquid. NOT TO BE USED less than 28 DAYS
before slaughter for human consumption.
Competition withholding period: The regulations of local racing or
competition authorities in your country should be observed.
Safety Directions: Product is harmful if absorbed by skin contact or
inhaled or swallowed. Avoid contact with eyes and skin. Do not inhale.
When using the product wear rubber gloves. After use and before
eating, drinking or smoking, wash hands, arms and face thoroughly
with soap and water. After each day’s use, wash gloves. Women of child
bearing age should take care to avoid contact with the solution.
